hrp0095p1-25 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Efficacy and safety of bisphosphonate treatment in pediatric patients with osteoporosis caused by immobilization

Lee Myeongseob , In Lee Hae , Seo Junghwan , Kim Ho-Seong

Introduction: Osteoporosis is medical condition commonly associated with immobilization in children, which can lead to a vicious cycle of disability, worsening osteoporosis, and recurrent fractures. Currently, bisphosphonates are widely used as a standard therapy in children with osteoporosis, but there are limited data on efficacy according to its dosage and duration. We aimed to evaluate efficacy of bisphosphonate treatment according to the dosage and durati...

hrp0097p1-316 | Growth and Syndromes | ESPE2023

The effects of androgen treatment on growth in patients with 5-α-Reductase type 2 deficiency

Kwon Ahreum , Kim Sujin , Seo Junghwan , in Lee Hae

Introduction: 5-α-Reductase type 2 deficiency (5αRD2) is 46,XY disorder of sex development that requires androgen treatment for normal male external genitalia development. Despite concerns regarding precocious puberty and stunted growth associated with androgen treatment, limited research has been conducted on its effects on individuals with 5αRD2. The present study aims to evaluate the impact of androgen treatment on bone age (BA) and height...